When human activities may lead to morally unacceptable harm that is scientifically plausible but uncertain, actions shall be taken to avoid or diminish that harm.
Morally unacceptable harm refers to harm to humans or the environment that is
- threatening to human life or health, or
- serious and effectively irreversible, or
- inequitable to present or future generations, or
- imposed without adequate consideration of the human rights of those affected.
Actions are interventions that are undertaken before harm occurs that seek to avoid or diminish the harm.
The PP requires that the main burden of providing evidence for safety rests on the proposers of a new technology or activity.